There are children in our communities and all across the country with a deadly childhood cancer, neuroblastoma (NB - the most common cancer among infants). These children are fighting for their lives—fewer than half will survive. When a child relapses the survival rate drops into the single digits and that is true when children are properly diagnosed. Unfortunately, up to a third aren't, causing them to be given the wrong treatments and worse. These children are our focus.
Treatments for these children can involve surgery, chemotherapy, radiation therapy, bone marrow transplants, and antibodies. Chemotherapy and radiation are themselves carcinogenic. If the child is fortunate enough to survive, the likelihood of dealing with long-term side effects is 72%, with 42% being life-threatening.
That is why harnessing the child’s own immune system is so important. Every one of the doctors on our medical advisory board is focused on training the immune system to fight cancer without toxic lifelong or life-threatening side effects. Obviously our first priority is to fund any treatment that can significantly increase survival rates; however, all things being equal we will lean towards harnessing the child's own immune system - like how a vaccine works.
CAR T-Cells, Autologous NK Cells + CH14.18, Natural Killer Cells Plus Humanized 3F8, T-Cell / Bispecific Antibody Trial (funding of the Liquid Biopsy Development Portion), Neuroblastoma Stem Cells - Identification and Destruction, Liquid Biopsy Development, and Bivalent Vaccine
Everything we have supported this far has been focused on harnessing the immune system to fight this disease. When a child is diagnosed with neuroblastoma anywhere in the country there is a very high probability that child will receive treatments developed by the doctors on our Medical Advisory Board. In addition, these doctors are keeping children alive with drugs designated for other diseases years before even clinical trials were opened to confirm the treatments effectiveness.
Children Are Dying Needlessly
Children are dying needlessly who could be saved with current treatments because their parents and attending physicians aren’t aware of them.
In addition, when frontline treatments fail, there are only a handful of centers that have the know how to deal with a relapse.
We have produced a free cancer guide, Steps to Hope, that teaches parents and caregivers how to find these leading centers focused on their child’s cancer, to confirm their child’s diagnosis, and to get treatment recommendations. Steps to Hope is available for free under the resource tab above.
The book shows also how to overcome the financial and emotional roadblocks that prevent many families from getting the life-saving treatments they need. The book is designed to benefit adults fighting cancer as well.
Steps to Hope, has been well received among former cancer patients and highly respected cancer professionals. Most notably, Dr. Siddhartha Mukherjee, Pulitzer Prize winning author of The Emperor of All Maladies, endorsed Steps to Hope and recommended it to Reader’s Digest.
The former President of the American Academy of Pediatrics, Dr. Fernando Stein, has endorsed it as well.
After sending a copy of Steps to Hope to then Vice President Joe Biden. we were invited to represent pediatric cancer research at the Cancer Moonshot Summit in Washington D.C.
None of this work would be possible without our donors.
Doris Roberts And Jack Betts Stand Up For Childhood Cancer And End Kids Cancer. (We changed our name).
An extremely powerful, and moving video that shows the challenges that families face fighting childhood cancer. Fourteen minutes long. The TV show 60 Minutes in Australia.